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急性心肌梗死诊断的生物化学指标中现阶段主要采用肌钙蛋白检测,心肌中存在肌钙蛋白T(Tn T)和肌钙蛋白I(Tn I),当AMI心肌出现损伤后血清中肌钙蛋白的水平开始逐渐升高,肌钙蛋白在血液中能够检测出一般在心肌损伤后的3~6h后,肌钙蛋白诊断窗口为3h-14d,如何能更早的预测AMI的发生,缩短治疗时间。根据临床观察及统计分析结果显示H-FABP检测在胸痛后3h内对心肌梗死诊断的敏感性、特异性均高于c Tn T。因此同肌钙蛋白相比,心型脂肪酸结合蛋白对于急性心肌梗死患者的早期诊断特别是胸痛时间在3h内较肌钙蛋白具有更高的特异性和敏感性,同时各项对于H-FABP的研究也提示其有较好的敏感性、特异性。
In the biochemical indexes of acute myocardial infarction, troponin T (Tn T) and troponin I (Tn I) were detected in myocardium at the present stage. Serum troponin The level of troponin began to increase, troponin in the blood can be detected generally 3 to 6 h after myocardial injury, troponin diagnostic window for 3h-14d, how to predict the occurrence of AMI earlier, shorten the treatment time . According to the results of clinical observation and statistical analysis, the sensitivity and specificity of H-FABP in the diagnosis of myocardial infarction within 3h after chest pain were higher than those of cTn. Therefore, compared with troponin, cardiac fatty acid-binding protein for early diagnosis of patients with acute myocardial infarction, especially chest pain within 3h than troponin with higher specificity and sensitivity, while the various for H-FABP Research also suggests that it has good sensitivity and specificity.