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目的初步探索饮水中高碘摄入是否与人群中血压异常升高存在流行病学关联。方法采用生态学研究和横断面调查研究的方法,比较高碘地区和对照地区居民血压水平差异,并且通过分层分析排除年龄、性别的影响;比较两地区血压异常检出率,得到居住地区与血压异常升高的RR值及其95%可信区间。结果高碘地区居民收缩压、舒张压、脉压水平均显著高于对照地区居民;高碘地区的血压异常检出率(33.08%)显著大于对照地区血压异常检出率(23.22%);高碘地区居民血压异常升高的RR值为1.48,RR95%可信区间为1.20～1.83。结论长期居住在高碘地区使血压异常升高的风险增加,高碘摄入可能是引起高血压患病风险增加的危险因素。
Objective To explore whether there is an epidemiological association between the high intake of iodine in drinking water and the abnormal increase of blood pressure in the population. Methods The methods of ecological research and cross-sectional investigation were used to compare the differences of blood pressure among residents in high iodine and control areas and to exclude age and sex through stratified analysis. The detection rate of abnormal blood pressure in both areas was compared to get the living area and RR of abnormally elevated blood pressure and its 95% confidence interval. Results The prevalence of systolic blood pressure, diastolic blood pressure and pulse pressure in residents with high iodine level were significantly higher than those in the control group. The prevalence of abnormal blood pressure in high iodine area (33.08%) was significantly higher than that in control area (23.22%). In the iodine area residents RR was 1.48, RR 95% confidence interval was 1.20-1.83. Conclusion Long-term living in areas with high iodine may increase the risk of abnormal blood pressure. High iodine intake may be the risk factor for the increased risk of hypertension.