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μ阿片受体（ MOR）是一种G蛋白偶联受体，在痛觉传导区以及与情绪和行为相关的区域广泛存在，影响着动物的神经反应和行为表现。有研究发现，MOR与抑郁情绪相关，并且与许多情绪相关的神经递质和大脑网络联系密切，彼此相互作用，共同对情绪调控产生作用。该文就MOR与抑郁症的相关性及研究进展予以综述。“,”μ-opioid receptor(MOR) is a kind of G protein coupled receptors,widespread in algesia transmission area and mood and behavior related area ,affecting the neural response and behavior of the ani-mals.Studies found that MOR is closely related to depression and it is closely associated with many emotions related neurotransmitters and brain network,which through the interactions regulates the mood.Here is to make a review of the research progress between depression and MOR.