Based on the case studies and statistical analysis of earthquake-related ionospheric disturbances mainly from DEMETER satellite,ground-based GPS and ionosounding data,this paper summarizes the statistical characteristics of earthquake-related ionospheric disturbances,including electromagnetic emissions,plasma perturbations and variation of energetic particle flux.According to the main results done by Chinese scientists, fusing with the existed study from global researches,seismo-ionospheric disturbances usually occurred a few days or hours before earthquake occurrence.Paralleling to these case studies,lithosphere-atmosphere-ionosphere (LAI) coupling mechanisms are checked and optimized.A thermo-electric model was proposed to explain the seismo-electromagnetic effects before earthquakes.A propagation model was put forward to explain the electromagnetic waves into the ionosphere.According to the requirement of earthquake prediction research,China seismo-electromagnetic satellite,the first space-based platform of Chinese earthquake stereoscopic observation system,is proposed and planned to launch at about the end of 2014.It focuses on checking the LAI model and distinguishing earthquake-related ionospheric disturbance.The preliminary design for the satellite will adopt CAST-2000 platform with eight payloads onboard.It is believed that the satellite will work together with the ground monitoring network to improve the capability to capture seismo-electromagnetic information,which is beneficial for earthquake monitoring and prediction researches. Based on the case studies and statistical analysis of earthquake-related ionospheric disturbances mainly from DEMETER satellite, ground-based GPS and ionosounding data, this paper summarizes the statistical characteristics of earthquake-related ionospheric disturbances, including electromagnetic emissions, plasma perturbations and variation of energetic particle flux. According to the main results done by Chinese scientists, fusing with the existed study from global researches, seismo-ionospheric disturbances due occurred a few days or hours before earthquake occurrence. Paralleling to these case studies, lithosphere-atmosphere-ionosphere (LAI ) coupling mechanisms are checked and optimized. A thermo-electric model was proposed to explain the seismo-electromagnetic effects before earthquakes. A propagation model was put forward to explain the electromagnetic waves into the ionosphere. Accreditation to the requirement of earthquake prediction research, China seismo-electromagnetic satellite, the firs t space-based platform of Chinese earthquake stereoscopic observation system, is proposed and planned to launch at about the end of 2014.It focuses on checking the LAI model and distinguishing earthquake-related ionospheric disturbance.The preliminary design for the satellite will adopt CAST- 2000 platform with eight payloads onboard. It is believed that the satellite will work together with the ground monitoring network to improve the capability to capture seismo-electromagnetic information, which is beneficial for earthquake monitoring and prediction researches.