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目的了解淮安市清浦区乡镇健康人群乙脑免疫水平,评价乙脑疫苗接种效果。方法2009—2011年,采用分层整群随机抽样的方法进行采样,采用空斑减少中和实验法进行检测。结果共采集合格标本1 092份,乙脑抗体阳性率为67.58%,抗体几何均数(GMT)为1∶11.89,各年度、各年龄组抗体阳性率间差异均有统计学意义(P<0.01)。结论清浦区健康人群乙脑抗体阳性率随年龄的增加而增长,小年龄组儿童抗体阳性率不高。对2岁以内儿童应及时给予乙脑疫苗的预防接种,同时做好查漏补种工作。
Objective To understand the level of Japanese encephalitis B-immunization among healthy population in township of Qingpu District, Huai’an City, and evaluate the effect of Japanese encephalitis B vaccine. Methods From 2009 to 2011, samples were stratified cluster random sampling method and detected by plaque reduction neutralization test. Results A total of 1 092 qualified samples were collected, the positive rate of JE antibody was 67.58%, and the geometric mean of antibody (GMT) was 1:11.89. The positive rate of antibody in each year and every group was statistically significant (P <0.01 ). Conclusion The positive rate of Japanese encephalitis B in healthy population of Qingpu District increases with the increase of age, while the positive rate of antibody in children of small age group is not high. Children within 2 years of age should be promptly given vaccination against JE vaccine, while doing a good job leak detection and replanting work.