论文部分内容阅读
本文报告了年龄大于12岁的32例急性淋巴细胞白血病患者的临床、血液学特征及其对治疗的反应,同时结合文献作预后因素分析。所有患者诱导治疗都给长春新碱(V)(1.6mg/m~2/周I.V×6剂)和(6-甲基)强地松龙(P)(40mg/m~2/每天,I.V×5周);其中有9例加用多诺霉素(D)(60mg/m~2/每次I.V隔天×3剂),另外10例加用环磷酰胺(C)(1500mg/m~24小时输注)和多诺霉素(D)(剂量同上)。所有患者除1例外均接
This article reports the clinical, hematological characteristics and response to treatment in 32 patients with acute lymphoblastic leukemia who are older than 12 years of age, and combined literature for prognostic factors. All patients received induction therapy with vincristine (V) (1.6 mg/m 2 /week IV x 6 doses) and (6-methyl) prednisolone (P) (40 mg/m 2 /day, IV ×5 weeks); 9 of them were treated with donomycin (D) (60mg/m~2/ every IV every other day × 3 doses), and 10 were added with cyclophosphamide (C) (1500mg/m ~ 24 hours infusion) and donomycin (D) (dose as above). All patients were excluded except 1 exception