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目的分析影响2型糖尿病视网膜病变(DR)的相关因素。方法对635例2型糖尿病患者的眼底、血压、HbA_1c、FPG、Cr、血尿酸及尿微量白蛋白/肌酐比(UACR)等临床资料进行回顾性分析。结果 2型糖尿病患者DR总患病率为23.9%,其中非增生性DR占20.6%,增生性DR占3.3%;DR患者的病程、HbA_1c、Cr、SBP、UACR和FPG均高于单纯DM患者(P<0.05);增生性DR患者的病程显著长于非增生性DR患者(P<0.01)。Logistic多元回归分析显示,病程是DR发病的独立危险因素。结论 DR与糖尿病病程、HbA_1c、Cr、SBP、UACR及FPG等的升高有关,病程是DR发生的重要危险因素。
Objective To analyze the related factors affecting type 2 diabetic retinopathy (DR). Methods The clinical data of fundus, blood pressure, HbA_1c, FPG, Cr, UAr and urinary albumin / creatinine ratio in 635 type 2 diabetic patients were analyzed retrospectively. Results The overall prevalence rate of DR was 23.9% in type 2 diabetic patients, including 20.6% for nonproliferative DR and 3.3% for proliferative DR. The course of disease, HbA1c, Cr, SBP, UACR and FPG in DR patients were higher than those in DM patients (P <0.05). The duration of proliferative DR was significantly longer than that of non-proliferative DR (P <0.01). Logistic multiple regression analysis showed that the course of disease was an independent risk factor for DR. Conclusions DR is associated with the course of diabetes, the increase of HbA 1c, Cr, SBP, UACR and FPG. The duration of DR is an important risk factor of DR.