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52例经病理组织学证实的肝细胞癌。对照组肝13例为尸检病例,均为突然死亡且无明显肝病者。取新鲜肝癌组织、癌周肝组织和对照肝组织各1～2g,用日立180—80型原子吸收分光光度计测定Mn、Cu、Zn、Fe Cd,同时取上述组织作常规石蜡切片,HE染色、地衣红染色等。结果:(1)Mn、Zn、Fe在肝癌周肝组织中的含量>对照组>癌组织,Cd在癌周肝>癌组织,均有统计学意义。这些过量的微量元素沉积在肝细胞内,可能对肝癌的肝病背景及其肝癌的病因
52 cases of histologically confirmed hepatocellular carcinoma. In the control group, 13 liver cases were autopsy cases, all of which were sudden death and no obvious liver disease. A total of 1 to 2 g of fresh HCC tissue, liver tissue surrounding the cancer, and control liver tissue were used. Mn, Cu, Zn, and Fe Cd were measured using a Hitachi 180-80 atomic absorption spectrophotometer. The above tissues were taken for routine paraffin sectioning and HE staining. , lichen red staining and so on. Results: (1) The contents of Mn, Zn and Fe in hepatic tissue of hepatocellular carcinoma were higher than that of control group> cancer tissue, and Cd was found in hepatic cancer> histologically significant. These excess trace elements are deposited in the liver cells and may be the background of the liver disease of liver cancer and the cause of liver cancer