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本文作者对181例病人进行了去T细胞移植,是迄今为止最大的一组去T细胞移植病人。经长期随访(平均5.5年),不仅对GVHD进行观察,对于加用蒽环类药物进行预处理对移植后果的影响、移植相关死亡率以及长期无病生存率也进行了详细观察。 材料与方法 1981年5月至1995年9月之间,共181例病人(男105例,女76例)进行了骨髓移植,其中急性髓性白血病第一次完全缓解(AML-CR1)者70例,第一次及第二次完全缓解的急性淋巴细胞白血病(ALL-CR1、ALL-CR2)共57例,首次慢性期慢粒白血
The authors performed decellularized T-cell transplantation on 181 patients and is by far the largest group of patients undergoing T-cell transplantation. After a long-term follow-up (mean, 5.5 years), not only GVHD was observed, but also the effects of pretreatment with anthracycline on transplantation outcomes, graft-related mortality, and long-term disease-free survival were also observed in detail. Materials and Methods Between May 1981 and September 1995, a total of 181 patients (male 105 and female 76) underwent bone marrow transplantation, among whom the first complete remission of acute myeloid leukemia (AML-CR1) 70 Cases, 57 cases of acute lymphoblastic leukemia (ALL-CR1, ALL-CR2) complete remission for the first time and second time, the first chronic phase chronic white blood