先锋必(cefoperazone)属于头孢菌素第三代药物,临床较多使用。常见不良反应为注射部位疼痛、静脉炎、发热、瘙痒、皮疹、厌食、恶心、呕吐、腹部绞痛、腹泻、低凝血酶原血症等,但引起严重低血压反应少见,现报道1例。 患者 男,48岁。因发热、咳嗽5天,于1992年11月30日入院。既往无高血压、心脏病及低血压病史。查体:体温39℃血压,14.7/10.7kPa(110/80mmHg)。神清,颈软。双肺呼吸音粗糙,左肺下部中、细湿啰音。心率128次/分,律齐, Pioneer will (cefoperazone) belong to the third generation cephalosporin drugs, more clinical use. Common adverse reactions were injection site pain, phlebitis, fever, itching, rash, anorexia, nausea, vomiting, abdominal cramps, diarrhea, low prothrombin hemorrhagic disease, but rare in patients with severe hypotension, is reported in 1 case. Male patient, 48 years old. Due to fever, cough for 5 days, on November 30, 1992 admission. No previous history of hypertension, heart disease and hypotension. Physical examination: body temperature 39 ℃ blood pressure, 14.7 / 10.7kPa (110 / 80mmHg). Clear, soft neck. Breathe sound rough lungs, the lower left lung, fine wet rales. Heart rate 128 beats / min, law Qi,