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血液灌流(Hemoperfusion)是一种新的治疗技术,其操作方法和血液透析相似,不同之处在于它是一种固—液两相物质转移的临床应用。即将病员的血液(液相)引出体外和固态的吸附剂(固相)接触,以吸附的方式清除某些内生的代谢产物或外源性的毒物,然后净化了的血液重新返回病人体内,从而起到治疗作用。血液灌流具有简便、高效、价廉等优点,近年来临床应用日趋广泛。在这个基础上,现在又发展了固定化酶血液灌流,即将特异性的酶固定化,以治疗某些酶缺乏症、淋巴瘤等,也可使某些代谢产物分解成无毒物质或转变成机体可利用的氨基酸。但这些工作目前尚处于实验阶段,临床应用为数很小。
Hemoperfusion is a new therapeutic technique that operates similarly to hemodialysis except that it is a clinical application of solid-liquid two-phase material transfer. The patient’s blood (liquid phase) leads out of the body and the solid adsorbent (solid phase) contact to adsorb the way to remove some endogenous metabolites or exogenous toxic substances, and then the purified blood back to the patient’s body, Thus play a therapeutic role. Hemoperfusion has the advantages of simple, efficient, inexpensive, clinical application in recent years, an increasingly widespread. On this basis, now has developed a fixed enzyme hemoperfusion, that is, specific enzyme immobilization to treat certain enzyme deficiency, lymphoma, etc., but also can make some metabolites into non-toxic substances or into Amino acids available to the body. However, these work is still in the experimental stage, the clinical application of a small number.