原发性痉挛性痛经是妇科常见病,但截止目前为止,仍缺乏较为安全特异的治疗方法。研究证实,原发痉挛性痛经可能与子宫内膜分泌的前列腺素过量有关(因前列腺素E和F能使子宫持续性收缩),近来Ylikorkala与Dawood也发现,痛经妇女的子宫内膜及经血内均含有高水平前列腺素。扑湿痛(甲灭酸Mefenamic Acid)不仅能抑制前列腺素的合成(主要抑制前列腺素合成的酶系统),又能抑制前列腺素的活性,所以,故对 Primary spastic dysmenorrhea is a common gynecological disease, but up to now, there is still a lack of more safe and specific treatment. Studies have shown that primary spastic dysmenorrhea may be related to endometrial secretion of prostaglandin excess (due to prostaglandin E and F can make uterine continuous contraction), recently Ylikorkala and Dawood also found that dysmenorrhea women’s endometrium and menstrual All contain high levels of prostaglandins. Pulsatile pain (Mefenamic Acid) not only inhibits prostaglandin synthesis (mainly inhibits prostaglandin synthesis of the enzyme system), but also inhibit prostaglandin activity, so