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结膜是眼表不可缺少的一部分,暴露于外易受到损伤,同时结膜自身也可能因肿瘤、变性以及自身免疫疾病而引起正常结构改变。因此需要有一种替代材料取代病变组织。目前临床上可选择的材料有很多,包括：自体或异体结膜、各种粘膜、Tenon’s膜、polytef异物膜、羊膜、细胞外基质以及羊膜联合结膜上皮细胞等,它们各具优、缺点。本文就近年来应用于临床或处于实验阶段的结膜替代材料做一综述。
Conjunctivalis is an integral part of the ocular surface, is exposed to the outside easily damaged, and conjunctiva itself may cause tumor, degeneration and autoimmune diseases caused by normal structural changes. Therefore, an alternative material is needed to replace diseased tissue. Currently available in many clinical materials, including: autologous or allo-conjunctiva, a variety of mucosa, Tenon’s membrane, polytef foreign body membrane, amniotic membrane, extracellular matrix and amniotic conjunctiva epithelial cells, which have their advantages and disadvantages. This review summarizes the conjunctival replacement materials that have been used clinically or experimentally in recent years.