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目的通过对上海市金山区社区居民进行大肠癌筛查,探讨社区居民大肠癌筛查的效果,为探索大肠癌筛查策略提供参考。方法对上海市金山区常住居民进行大肠癌筛查。采用问卷调查结合粪便隐血试验(fecal occult blood test,FOBT)的两步筛查模式,初筛阳性者行全结肠镜检查,并对结果进行分析。结果完成初筛58 215人,初筛完成率99.07%,初筛阳性率25.44%,肠镜依从性41.87%,大肠癌检出率0.45%,腺瘤检出率46.40%,总病变检出率35.74%,男女间检出率差异有统计学意义(x~2=224.337,P<0.001),随着年龄的增大,检出率不断上升,各年龄组间检出率差异有统计学意义(x~2=37.788,P<0.001)。结论大肠癌筛查能有效地检出居民大肠癌及腺瘤等病变,对于大肠癌的早发现、早诊断、早治疗有重要意义。
Objective To explore the effect of colorectal cancer screening among community residents in community residents in Jinshan District, Shanghai, and to provide reference for exploring screening strategies for colorectal cancer. Methods The routine screening of colorectal cancer in Jinshan District of Shanghai was conducted. A two-step screening model based on questionnaire combined with fecal occult blood test (FOBT) was used. The patients who screened positive were followed by colonoscopy and the results were analyzed. Results A total of 58 215 primary screening tests were completed, with a primary screening rate of 99.07%, a primary screening rate of 25.44%, a colonoscopy compliance of 41.87%, a colorectal cancer detection rate of 0.45%, a adenoma detection rate of 46.40%, a total detection rate of total lesions 35.74%. There was a significant difference in the detection rate between men and women (x ~ 2 = 224.337, P <0.001). With the increase of age, the detection rate increased continuously and the detection rate was significantly different among all age groups (x ~ 2 = 37.788, P <0.001). Conclusion Colorectal cancer screening can effectively detect the resident colorectal cancer and adenoma and other lesions, for early detection, early diagnosis and early treatment of colorectal cancer is of great significance.