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目的探讨上海市闵行区恶性肿瘤患者生存情况,为制定恶性肿瘤防制策略提供科学依据。方法根据上海市肿瘤登记系统中登记的2002-2005年闵行区户籍新发病例及其随访资料,获得其发病与生存资料,采用简略寿命表法计算期望生存概率,EdererⅡ法估计累积期望生存概率,Log-rank检验法比较两组间生存率。结果闵行区2002-2005年共登记新发恶性肿瘤11 455例,发病率为381.98/10万,5年观察生存率(OSR)为35.58%,相对生存率(RSR)为47.60%,胰腺癌5年RSR最低,仅为4.85%,为闵行区致死风险最高的癌种。肺癌、肝癌、胆囊癌5年RSR<20%。男性前列腺癌5年OSR最高(OSR:53.39%,RSR:90.07%),胰腺癌最低(OSR:2.31%,RSR:3.27%);其次为肺癌(OSR:9.89%,RSR:14.14%)、肝癌(OSR:10.51%,RSR:13.00%)。女性子宫体癌5年生存率最高(OSR:83.13%,RSR:93.19%),胰腺癌最低(OSR:4.37%,RSR:6.94%),女性较男性更易患胆囊癌且生存情况不理想(OSR:7.65%,RSR:12.03%);女性肿瘤5年生存情况好于男性,差异有统计学意义(χ2=253.186,P<0.01)。结论闵行区整体生存率高于国内多个城市,与国外相比仍有较大差距,需进一步分析生存影响因素。
Objective To investigate the survival of patients with malignant tumors in Minhang District of Shanghai and to provide scientific evidence for the development of strategies for the prevention and treatment of malignant tumors. Methods According to the newly registered cases and their follow-up data registered in Shanghai Tumor Registry from 2002 to 2005 in Minhang District, the incidence and survival data were obtained. The life expectancy was calculated by the simple life table method. The cumulative survival rate was estimated by EdererⅡmethod. Log-rank test was used to compare the survival rates between the two groups. Results A total of 11 455 newly diagnosed malignant tumors were registered in Minhang District from 2002 to 2005, with an incidence of 381.98 / 100 000. The 5-year OSR was 35.58%, the relative survival rate (RSR) was 47.60%, and pancreatic cancer 5 The lowest annual RSR was only 4.85%, the highest risk of death in Minhang district of cancer. Lung cancer, liver cancer, gallbladder cancer 5 years RSR <20%. The 5-year OSR of male prostate cancer was the highest (OSR: 53.39%, RSR: 90.07%), the lowest was pancreatic cancer (OSR: 2.31%, RSR: 3.27%), followed by lung cancer (OSR: 9.89%, RSD: 14.14% (OSR: 10.51%, RSR: 13.00%). The 5-year survival rates of female uterine body cancer were the highest (OSR 83.13%, RSR 93.19%) and lowest in pancreatic cancer (OSR 4.37%, RSR 6.94%). Women were more likely to suffer from gall bladder cancer than men and had poor survival (OSR : 7.65%, RSR: 12.03%). The 5-year survival rate of female tumors was significantly higher than that of males (χ2 = 253.186, P <0.01). Conclusion The overall survival rate of Minhang District is higher than that of several cities in China, and there is still a long way to go compared with that of other countries. It is necessary to further analyze the influencing factors of survival.