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食管癌(esophageal cancer,EC)、胃癌(gastric cancer,GC)是消化系统最常见的恶性肿瘤,居我国恶性肿瘤病死率之首。由于大多数患者在确诊时已达进展期,传统的手术及放化疗预后不佳,分子靶向治疗是近年来肿瘤治疗领域中的研究热点,已在癌症治疗中显示出高效、低毒等特点。本文参考近年来的文献并根据细胞获得能力的类型将靶向药物分为五个不同类型进行分析,为EC、GC治疗提供依据。
Esophageal cancer (EC) and gastric cancer (GC) are the most common malignant tumors in the digestive system, ranking the first among the malignant tumors in China. Since most patients have reached the advanced stage of diagnosis and the poor prognosis of traditional surgery and radiotherapy and chemotherapy, molecular targeted therapy has been a hot spot in the field of cancer therapy in recent years and has been shown to be highly effective and has low toxicity in cancer treatment . In this paper, based on the literature in recent years and based on the types of cell acquisition ability of the targeted drugs are divided into five different types of analysis for the EC, GC provide the basis for treatment.