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本文观察前列地尔与氯吡格雷联合治疗不稳定性心绞痛(UAP)的临床疗效及对血液流变学及血脂的影响。结果表明,治疗组临床症状及心电图总有效率均优于对照组(P<0.05)。治疗组治疗后纤维蛋白原、血浆粘度、胆固醇及甘油三酯均较治疗前明显下降(P<0.01,P<0.05),其中纤维蛋白原及血浆粘度治疗组较对照组改善尤为显著(P<0.01)。认为前列地尔与氯吡格雷联合治疗不稳定性心绞痛疗效显著,且能降低血粘度及纤维蛋白原而无出血现象发生,值得临床推广应用。
This article observes the prostaglandin and clopidogrel in the treatment of unstable angina pectoris (UAP) clinical efficacy and hemorrheology and blood lipids. The results showed that the clinical symptoms of the treatment group and the total effective rate of ECG were better than the control group (P <0.05). The fibrinogen, plasma viscosity, cholesterol and triglyceride in the treatment group were significantly lower than those before treatment (P <0.01, P <0.05), and the fibrinogen and plasma viscosity treatment group improved more significantly than the control group (P < 0.01). That the alprostadil and clopidogrel combined treatment of unstable angina significant effect, and can reduce blood viscosity and fibrinogen without bleeding, worthy of clinical application.