移植物抗宿主病(GvHD)是导致骨髓移植(BMT)后发病和死亡的主要原因。为了识别其早期临床、实验室或组织病理学上发展为进行性致死性 GvHD 的指标,作者对69例接受同种骨髓移植后而发生 GvHD 的病人进行了研究。这69例均因患各种急、慢性白血病,再生障碍性贫血,何杰金病,多发性骨髓瘤等而需要 BMT 治疗。年龄均在3～55 Graft versus host disease (GvHD) is the leading cause of morbidity and mortality following bone marrow transplantation (BMT). In order to identify early clinical, laboratory or histopathological development of GVHD as a marker of lethality, the authors studied 69 patients who developed GvHD after allogeneic bone marrow transplantation. These 69 patients are suffering from various acute and chronic leukemia, aplastic anemia, Hodgkin’s disease, multiple myeloma and need BMT treatment. The ages are in 3 ~ 55