论文部分内容阅读
摘要目的确定CT灌注成像能否显示抗血管生成药物治疗肺癌后的早期血流灌注改变,从而预测治疗反应。方法将非小细胞肺癌病人分成2组,第1组17例,第2组23例;其中第1组病人接受常规化疗及抗血管内皮生长因子治疗,第2组病人接受常规化疗,2组均在接受化疗前(TIME0)、第1个化疗周期(TIME1)结束后、第3个化疗周期(TIME2)和第6个化疗周期(TIME3)结束后分别行CT灌注扫描。评价的CT扫描参数包括:①总的肿瘤血管容积(TVV)和总的肿瘤
Abstract Objective To determine whether CT perfusion imaging can predict the early response of perfusion after anti-angiogenic drug treatment of lung cancer. Methods The patients with non-small cell lung cancer were divided into 2 groups: 17 cases in group 1 and 23 cases in group 2, in which group 1 received conventional chemotherapy and anti-VEGF, group 2 received routine chemotherapy, The CT perfusion scan was performed before TIME0, after the first chemotherapy cycle (TIME1), after the third chemotherapy cycle (TIME2) and the sixth chemotherapy cycle (TIME3). The CT scan parameters evaluated included: Total tumor volume (TVV) and total tumor