论文部分内容阅读
目的:探讨采用不同剂量的丹参注射液联合波尼松龙治疗口腔粘膜下纤维性病的治疗效果,为今后的治疗提供更多的依据。方法:选择从2010年1月至2013年1月期间在我院口腔科治疗的100例口腔粘膜下纤维性病患者,根据门诊号,随机将患者分为低剂量组、次低剂量组、中剂量组、高剂量组和对照组,每组各20例,低剂量组、次低剂量组、中剂量组、高剂量组,分别使用不同剂量丹参注射液联合波尼松龙治疗,对照组单纯使用波尼松龙治疗,观察治疗一个疗程后患者口腔粘膜情况及张口度。结果:中剂量组和高剂量组情况改善要明显好于低剂量、次低剂量组、对照组,差异具有显著性(P<0.05)。结论:丹参注射液联合泼尼松龙治疗口腔粘膜下纤维性病疗效令人满意,其中低剂量丹参注射液便有效果,一定范围内剂量越高,疗效越好,值得在临床推广。
Objective: To investigate the treatment effect of oral administration of Danshen injection combined with prednisolone on oral submucous fibrosis and to provide more basis for the future treatment. Methods: From January 2010 to January 2013 in our hospital dental treatment of 100 cases of oral submucous fibrosis patients, according to the number of patients were randomly divided into low-dose group, sub-low dose group, medium dose Group, high dose group and control group, 20 cases in each group, low dose group, second low dose group, middle dose group and high dose group were treated with different doses of Salvia injection combined with prednisolone, the control group simply used The treatment of prednisolone, observe the treatment of a course of oral mucosa and mouth conditions. Results: The improvement in middle dose group and high dose group was significantly better than that in low dose group, sub-low dose group and control group (P <0.05). Conclusion: Salvia miltiorrhiza injection combined with prednisolone treatment of oral submucous fibrosis is satisfactory, including low-dose salvia miltiorrhiza injection has an effect, the higher the dose within a certain range, the better the effect is worth in the clinical promotion.