作者报告６例溃疡病急性大出血行远端胃大部切除术后再发上消化道出血，经胃镜证实为急性胃粘膜病变（ＡＧＭＬ），着重对术后ＡＧＭＬ的发病机理、诱发因素、好发部位及治疗方法等资料进行了分析讨论。认为在低血压状况下行急诊胃大部切除术易导致术后ＡＧＭＬ，诊断上应注意与胃术后吻合口出血相鉴别。治疗本病以综合性保守治疗为主，提出洛赛克（Ｌｏｓｅｃ）是治疗本病疗效可靠的药物之一。 The authors report 6 cases of acute hemorrhagic peptic ulcer disease after distal gastrectomy and upper gastrointestinal bleeding confirmed by gastroscopy for acute gastric mucosal lesions (AGML), focusing on postoperative AGML pathogenesis, predisposing factors, good hair Site and treatment methods and other data were analyzed and discussed. That under the condition of hypotension in emergency gastrectomy can easily lead to postoperative AGML, diagnosis should pay attention to and postoperative gastroesophageal anastomotic bleeding phase identification. Treatment of the disease with a comprehensive conservative treatment based, proposed Losec (Losec) is the treatment of the disease and reliable one of the drugs.