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目的探讨三亚市健康体检妇女子宫颈人乳头瘤病毒感情情况,为预防感染提供临床资料。方法从2009年3月-2011年11月在三亚市人民医院体检的、在三亚市居住半年以上的18~59岁健康女性中随机选取1 260例为研究对象,对所有患者进行液基细胞学检查及第2代杂交捕获检测,若发现异常细胞,并对宫颈进行活检,将所有体检者检测结果进行统计学分析。结果经检测,不同年龄组HPV感染情况分别为18~24岁阳性率10.99%,25~34岁阳性率23.52%,35~44岁阳性率18.22%,45~59岁阳性率19.16%,差异有统计学意义(P<0.05)。宫颈病变病例中CIN I型占66.67%,CINⅡ型占22.62%,CINⅢ型占8.33%,宫颈癌占2.38%。HPV阳性中感染最多的是HPV16、52、58型。结论本地女性HPV感染率较高,其中HPV16、52、58是本地女性HPV感染最常见的3种亚型。
Objective To investigate the affection of cervix human papillomavirus (HPV) in healthy physical examination in Sanya City and provide clinical data for the prevention of infection. Methods From January 2009 to November 2011 in Sanya City People’s Hospital physical examination in Sanya City, living more than six months of healthy women aged 18 to 59 years were randomly selected 1 260 as the research object, all patients were liquid-based cytology Inspection and second generation hybridization capture detection, if abnormal cells are found, and biopsy of the cervix, the results of all the physical examination for statistical analysis. Results The positive rates of HPV infection in different age groups were 18.22% and 18.22% respectively. The positive rate of HPV infection was 18.22% at 25-34 years, 19.16% at 35-44 years, and the positive rate was 19.16% Statistical significance (P <0.05). Cervical lesions in CIN I accounted for 66.67%, CIN Ⅱ accounted for 22.62%, CIN Ⅲ accounted for 8.33%, cervical cancer accounted for 2.38%. HPV-positive in the most infected is HPV16, 52,58 type. Conclusion The prevalence of HPV in local women is high, among which HPV16, 52 and 58 are the most common subtypes of HPV among local women.