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应用一种简便的肝脏贮备功能试验—肝促凝血活酶试验(HPT)检查218例急性血吸虫病,64例慢性血吸虫病及62例晚期血吸虫病。结果表明:73%的急性血吸虫病病人HPT活动度降低,经吡喹酮治疗后1个月98%的病例HPT活动度恢复正常;92.2%的慢性血吸虫病病人HPT活动度均在正常范围内;98.4%的晚期血吸虫病病人HPT活动度均显著降低,虽经呲喹酮和/或对症治疗,2个月后均未恢复正常。提示急性血吸虫病人的肝脏贮备功能减低是可逆的,而晚期血吸虫病人则不然。
218 cases of acute schistosomiasis, 64 cases of chronic schistosomiasis and 62 cases of advanced schistosomiasis were examined with a simple liver function test - hepatic thromboplastin test (HPT). The results showed that the activity of HPT decreased in 73% of acute schistosomiasis patients, and the activity of HPT returned to normal in 98% of cases after 1 month of praziquantel treatment. The activity of HPT in 92.2% of chronic schistosomiasis patients was within the normal range. In 98.4% patients with advanced schistosomiasis, the activity of HPT was significantly lower than that without methadone and / or symptomatic treatment and did not return to normal after 2 months. Tip acute schistosomiasis patients with liver reserve function is reversible, while patients with advanced schistosomiasis is not.