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目的对比分析胰岛素不同给药途径治疗糖尿病酮症酸中毒患者的疗效,旨在提高治疗效果。方法将2010年1月-2012年6月我院糖尿病酮症酸中毒患者54例随机分为观察组和对照组各27例。对照组采用多次胰岛素皮下注射,观察组患者给予短期持续性皮下胰岛素输注,分析比较两组患者胰岛素使用剂量和酮症控制情况等。结果观察组的血糖达标时间、血酮恢复时间、尿酮恢复时间和低血糖发生次数均低于对照组,t检验显示,两组血酮恢复时间、尿酮恢复时间和低血糖发生次数间差异均具有统计学意义(P<0.05)。结论对于2型糖尿病患者进行多次胰岛素皮下注射,能够较好的控制胰岛素水平,并能够缩短血酮和尿酮恢复时间,降低低血糖的发生次数。
Objective To compare and analyze the curative effect of different administration routes of insulin on diabetic ketoacidosis patients and to improve the therapeutic effect. Methods From January 2010 to June 2012, 54 patients with diabetic ketoacidosis in our hospital were randomly divided into observation group (27 cases) and control group (27 cases). In the control group, multiple subcutaneous injections of insulin were administered. Patients in the observation group were given short-term sustained subcutaneous insulin infusion. The insulin dosage and ketosis control were compared between the two groups. Results The observation group’s blood glucose up-time, blood ketone recovery time, urine ketone recovery time and the number of hypoglycemia were lower than the control group, t test showed that the two groups of blood ketone recovery time, urine ketone recovery time and the number of occurrence of hypoglycemia were Statistical significance (P <0.05). Conclusions Multiple subcutaneous insulin in patients with type 2 diabetes can control the insulin level better, and can shorten the recovery time of blood ketone and urinary ketone and reduce the incidence of hypoglycemia.