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目的探讨短暂性脑缺血发作(transient ischemic attack,TIA)患者ABCD2评分与血清TNF-α的关系。方法按照ABCD2评分将150例TIA患者划分为低危(0～3分)、中危(4～5分)和高危(6～7分)三组,并比较各组患者血清TNF-α平均水平的差异。结果三组TNF-α水平差异具有统计学意义(P<0.05)。ABCD2评分法+TNF-α和AB-CD2评分法的曲线下面积(95%CI)分别为0.753(0.661-0.869)和0.646(0.604-0.705)(P<0.05)。结论 TIA患者ABCD2评分与TNF-α正相关,ABCD2评分法+TNF-α的临床价值高于单纯ABCD2评分法。
Objective To investigate the relationship between ABCD2 score and serum TNF-α in patients with transient ischemic attack (TIA). Methods According to the ABCD2 score, 150 TIA patients were divided into three groups: low risk (0-3), intermediate risk (4-5) and high risk (6-7), and the mean serum levels of TNF- The difference. Results The difference of TNF-α level among the three groups was statistically significant (P <0.05). The area under the curve (95% CI) of the ABCD2 scoring + TNF-alpha and AB-CD2 scoring were 0.753 (0.661-0.869) and 0.646 (0.604-0.705) respectively (P <0.05). Conclusion The ABCD2 score of TIA patients is positively correlated with TNF-α. The clinical value of ABCD2 score + TNF-α is higher than that of ABCD2 score alone.