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目的：为了进一步探讨临床有效控制院内感染的护理干预措施和方法。方法本次研究选取2013年10~12月我院住院部收治的各类患者88例为研究对象，对其临床护理干预经验进行总结分析。结果①感染发生时间组间比较，常规干预组患者的感染发生时间明显早于针对性干预组，数据统计学比较结果显示差异显著（<0.05）；②感染发生率组间比较，常规干预组患者的感染发生率显著高于针对性干预组，数据统计学比较结果显示差异显著（<0.05）；③比较两组患者的住院时间和住院费用，针对性干预组患者的住院时间和住院费用均明显低于常规干预组，其数据统计学比较结果显示差异显著（<0.05）。结论在临床针对住院患者实施护理干预的实践过程中，与传统的常规护理干预措施相比较，采用针对性护理干预措施可有效的控制患者院内感染，缩短患者的住院时间，节省患者的治疗费用，是临床针对住院患者实施护理的理想选择方案之一。“,”Objective To further explore the care interventions and methods for the clinical effective control of nosocomial infections. Methods 88 patients with various types in our hospital from October 2013 to December 2013 were chosen as the research object. The clinical experiences of nursing interventions were summarized and analyzed. Results ①The infection time compared between the two groups, the infection time of the routine intervention group was earlier than the targeted intervention group, and the statistical data comparison results showed the differences were significant ( <0.05).②The incidence of infection compared between the two groups, the incidence of infection in the conventional intervention group was significantly higher than the targeted intervention group, and the statistical data comparison results showed the differences were significant ( <0.05).③The length of stay and hospital costs between the two groups were compared, the length of stay and hospital costs in the targeted intervention group were significantly lower than the conventional treatment group, and the statistical data comparison results showed the differences were significant ( <0.05). Conclusion In the clinical practice of nursing intervention for hospitalized patients, compared with the conventional routine care interventions, the use of targeted nursing interventions can effectively control nosocomial infection, shorten hospital stays of patients, and save the cost of treatment of patients. It is the ideal program for clinical care of hospitalized patients.