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盐水灌洗腹腔可以清除细菌和某些能助长细菌感染的物质,如胆汁、粘液、血液等。但盐水本身在腹腔内可损害嗜中性白细胞的吞噬作用。研究盐水灌洗的功效必须有一种在腹腔内表现类似细菌而又无害的标示物。为这个目的,我们以~(99)锝标记的1μm直径的人体血清蛋白中心体注入两种动物的腹肚内,并与同时注入的大肠杆菌的回收液作比较。在确立了中心体是满意的细菌模型后,我们再在人体上进行前瞻性的腹腔灌洗研究。材料和方法动物研究——用标有~(99)得的中心体接种物(2ml中约含10~9)和已测知
Saline lavage the abdominal cavity can remove bacteria and some substances that can contribute to bacterial infection, such as bile, mucus, blood and so on. However, saline itself can impair the phagocytosis of neutrophils in the abdominal cavity. To study the efficacy of saline lavage, there must be a marker that behaves like a bacteria in the abdominal cavity that is harmless. To this end, we injected the abdomen of both animals with a centimeter of ~ (99) technetium labeled human serum protein centrosome and compared with the concurrently injected Escherichia coli recovery solution. After establishing a bacterial model with a central body that is satisfactory, we then conduct a prospective study of peritoneal lavage on the human body. MATERIALS AND METHODS Animal studies - Inoculation of the centrosome inoculum marked with (99) (10 to 9 in 2 ml) and measured