论文部分内容阅读
目的观察延寿抗衰胶囊治疗脑血管病前后ＳＯＤ活性及ＬＰＯ含量的变化。方法应用羟胺法及丙二醛法检测３４例老年脑血管病患者血清中ＳＯＤ活性及ＬＰＯ含量，同时还检测了血液流变学指标。结果ＳＯＤ活性治疗后（１８１．４±１７．８）明显高于治疗前（１１９．６±１８．２）（Ｐ＜０．０５），ＬＰＯ含量明显低于治疗前（４．０３±０．８２，５．２４±０．９４）（Ｐ＜０．０５）。全血粘度治疗后降低（４．０７±１．０２，５．２３±０．９２）（Ｐ＜０．０１）；红细胞电泳速度增快（２８．３４±６．７１，１９．３５±３．９６）（Ｐ＜０．０１）。结论延寿抗衰胶囊能够提高脑血管病患者的ＳＯＤ活性，降低ＬＰＯ含量，改善血液流变性。
Objective To observe the changes of SOD activity and LPO content of Yanshou Kang Capsule before and after treatment of cerebrovascular diseases. Methods Hydroxylamine and malondialdehyde were used to detect the activity of SOD and the content of LPO in 34 senile patients with cerebrovascular disease and the indexes of hemorrheology were also tested. Results The SOD activity was significantly higher after treatment (181.4 ± 17.8) than before treatment (119.6 ± 18.2) (P <0.05), and the LPO content was significantly lower than that before treatment (4.03 ± 0. 82, 5.24 ± 0.94) (P <0.05). The whole blood viscosity decreased (4.07 ± 1.02,5.23 ± 0.92) (P <0.01) and the erythrocyte electrophoresis speed increased (28.34 ± 6.71 and 19.35 ± 3 .96) (P <0.01). Conclusion Yanshou Kang Capsule can improve the activity of SOD in patients with cerebrovascular disease, reduce the content of LPO and improve the blood rheology.