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目的:探讨临床疾病与外周血染色体异常的关系。方法:对2051例遗传咨询有疑问者进行外周血淋巴细胞培养,进行染色体检查,G显带,进行核型分析。结果:2051例查出染色体异常的核型200例,异常率9.75%。结论:染色体异常与临床疾病发生有关,遗传咨询与产前诊断在临床治疗及指导优生优育中意义重大。
Objective: To investigate the relationship between clinical diseases and chromosomal abnormalities in peripheral blood. Methods: Totally 2051 cases of genetic counseling were asked about the peripheral blood lymphocyte culture, chromosome examination, G banding and karyotype analysis. Results: 2051 karyotypes were detected in 200 cases, the abnormal rate was 9.75%. Conclusion: Chromosomal abnormalities are related to the occurrence of clinical diseases. Genetic counseling and prenatal diagnosis are of great significance in clinical treatment and guidance of prenatal and postnatal care.