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目的观察肺腺癌术后辅助化疗的疗效以及护理干预对化疗不良反应的影响。方法肺腺癌患者108例,术后采用辅助化疗。随访并评估疗效和护理干预对化疗不良反应如恶心呕吐、骨髓抑制、肾脏功能损害的影响。结果患者术后1年及2年总生存率分别为95.4%和87.0%,中位无疾病进展期为19.8个月。合理的护理能有效地减轻化疗不良反应。结论肺腺癌术后的辅助化疗有利于延长生存时间,化疗期间合理有效的护理能减少不良反应的发生,提高患者的生存质量。
Objective To observe the effect of postoperative adjuvant chemotherapy for lung adenocarcinoma and the effect of nursing intervention on adverse reactions of chemotherapy. Methods A total of 108 patients with lung adenocarcinoma were treated with adjuvant chemotherapy. Follow-up and assessment of efficacy and nursing intervention on adverse reactions such as chemotherapy, nausea and vomiting, bone marrow suppression, renal dysfunction. Results The overall 1-year and 2-year postoperative survival rates were 95.4% and 87.0%, respectively. The median progression-free disease duration was 19.8 months. Reasonable care can effectively reduce the adverse reactions of chemotherapy. Conclusions Adjuvant chemotherapy after lung adenocarcinoma is beneficial to prolong the survival time. Reasonable and effective nursing during chemotherapy can reduce the incidence of adverse reactions and improve the quality of life of patients.