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食管静脉曲张破裂大出血(EVB)是肝硬化门脉高压常见的并发症,病死率高达50％。1996年以来,我院应用奥曲肽(Sandostatin,商品名善得定)治疗EVB 12例,疗效满意,现报告如下。 1.临床资料 EVB 12例,男8例,女4例,年龄37～70岁,平均58例。临床表现为呕血或便血,出血量在1000ml以上,收缩压≤13.3kPa,心率≥100次/分。其中肝炎后肝硬化10例,酒精性及原因不明肝硬化各1例。8例有EVB史。8例于用药前12小时内经胃镜证实诊断,4例胃镜检查在用药后12小时内进行。所有病人用药前12小时内均未用过其它止血药。
Esophageal variceal bleeding (EVB) is a common complication of cirrhotic portal hypertension with a mortality rate of up to 50%. Since 1996, our hospital application of octreotide (Sandostatin, trade name Zenadine) treatment of 12 cases of EVB, with satisfactory results, are as follows. 1. Clinical data 12 cases of EVB, 8 males and 4 females, aged 37 to 70 years, an average of 58 cases. Clinical manifestations of hematemesis or blood in the stool, bleeding in more than 1000ml, systolic blood pressure ≤ 13.3kPa, heart rate ≥ 100 beats / min. Including hepatitis cirrhosis in 10 cases, alcoholic and unexplained liver cirrhosis in 1 case. 8 cases had EVB history. 8 cases were diagnosed by gastroscope within 12 hours before treatment and 4 cases were examined within 12 hours after treatment. No other hemostatic agents were used in all patients within 12 hours before treatment.