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我们应用国产单磷酸阿糖腺苷(Ara—AMP)联合乙肝疫苗治疗慢性乙型肝炎30例,取得了较好疗效,现报道如下.1.材料与方法病例选择:所有病例均为住院的慢性乙肝患者,按1990年上海会议制定的标准诊断和分型.治疗组(组1)30例,半年内未曾抗病毒或皮质激素治疗.α-2b干扰素合用无环鸟苷(ACV)组(组2)28例(2例因严重副反应而中止治疗未列入),护肝药组(组3)30例.三组在年龄、性别、病型、肝功能及HBVM方面皆有可比性.
We apply the domestic production of Ara-AMP monotherapy with hepatitis B vaccine in patients with chronic hepatitis B in 30 cases, and achieved good results, are reported as follows.1.Material and methods of patient selection: all cases were hospitalized chronic Hepatitis B patients were diagnosed and classified according to criteria established by the Shanghai Conference in 1990. Thirty patients in the treatment group (group 1) had no antiviral or corticosteroid treatment within six months.α-2b interferon plus acyclovir (ACV) group Group 2) 28 patients (2 patients discontinued treatment due to serious side effects were not included), Liver Protection Group (Group 3) 30 patients.The three groups were comparable in age, gender, disease type, liver function and HBVM .