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目的探讨患者胸腔积液与血清中的CEA(癌胚抗原)、CA12-5(糖类蛋白12-5)水平及其比值(胸腔积液/血清)对肺部良、恶性胸腔积液诊断价值。方法采用电化学发光免疫法检测76例胸腔积液患者胸腔积液与血清CEA、CA12-5水平及其比值分析。结果恶性组患者胸腔积液与血清的CEA、CA12-5水平及其比值均明显高于良性组,两组差异有统计学意义。结论检测患者胸腔积液与血清CEA、CA12-5水平及其比值对于鉴别患者胸腔积液的性质有指导性意义。
Objective To investigate the diagnostic value of pleural effusion and serum CEA (carcinoembryonic antigen), CA12-5 (carbohydrate protein 12-5) and its ratio (pleural effusion / serum) in the diagnosis of benign and malignant pleural effusion in lung . Methods Electrochemiluminescence immunoassay was used to detect pleural effusion, serum CEA and CA12-5 in 76 patients with pleural effusion and their ratio analysis. Results The malignant group of patients with pleural effusion and serum CEA, CA12-5 levels and the ratio were significantly higher than the benign group, the difference between the two groups was statistically significant. Conclusion Detection of pleural effusion and serum CEA, CA12-5 levels and their ratio for the identification of pleural effusion in patients with the nature of the significance.