2000年 7月下旬至 8月中旬在山东威海南圈水库网箱养殖的奥尼罗非鱼发病严重。病鱼在网箱表面活动滞缓，不摄食，精神萎顿，体色暗淡，鳃丝腐烂，肛门红肿。最初认为是缺氧、烂鳃和肠炎并发症，采取增氧，氯消毒剂进行水体鱼体消毒，投喂呋喃唑酮药饵等措施，但病情仍未好转。 In late July 2000 to mid-August in Shandong Weihai Nanquan reservoir caged Tilapia Tilapia serious. Diseased fish in the surface of the cage activity stagnant, do not feed, mental exhaustion, body color dim, gill filarial rot, anal swelling. Initially considered to be hypoxia, rotten gill and enteritis complications, to take oxygen, chlorine disinfectant disinfection of water fish, feeding furazolidone bait and other measures, but the condition has not improved.