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目的:探讨异位妊娠中选择甲氨蝶呤以及米非司酮的有效性。方法:选取该院2013年2月至2015年8月152例异位妊娠患者,数字抽取分成观察组与对照组,对照组予以米非司酮,观察组经甲氨蝶呤、米非司酮联合治疗,对比两组治疗效果、住院时间、包块大小、血β-绒毛膜促性腺激素(β-HCG)值变化及不良反应。结果:观察组总有效率92.11%明显高于对照组72.37%(P<0.05);观察组住院时间明显短于对照组(P<0.05);观察组治疗后包块大小、血β-HCG值均少于对照组(P<0.05);不良反应发生率无显著差异(P>0.05)。结论:异位妊娠中选择甲氨蝶呤及米非司酮具有明显效果,减小包块,改善β-HCG,值得临床应用。
Objective: To investigate the efficacy of methotrexate and mifepristone in ectopic pregnancy. Methods: A total of 152 patients with ectopic pregnancy were selected from February 2013 to August 2015 in our hospital. The patients in the ectopic pregnancy were divided into the observation group and the control group. The control group was given mifepristone. The patients in the observation group were treated with methotrexate, mifepristone Combined treatment, the two groups were compared the treatment effect, length of stay, mass size, blood β-HCG value and adverse reactions. Results: The total effective rate in the observation group was 92.11%, significantly higher than that in the control group (72.37%, P <0.05). The length of stay in the observation group was significantly shorter than that in the control group (P <0.05) (P <0.05). There was no significant difference in the incidence of adverse reactions between two groups (P> 0.05). Conclusion: Methotrexate and mifepristone have obvious effect in ectopic pregnancy, reducing the mass and improving β-HCG, which is worthy of clinical application.