论文部分内容阅读
目的 探讨月经周期不同阶段手术及预后的关系。方法 对月经周期不同分期 (卵泡期、黄体期及围排卵期和围月经期 )分别测定其血清泌乳素、雌二醇和孕酮的浓度 ,了解其与 3、5年生存期的关系。结果 (1)围排卵期及黄体期血清孕酮含量明显增高 ;(2 )围排卵期 3、5年生存率均高 ;(3)黄体期 3年生存率高 ,而 5年生存率无差异。结论 乳腺癌病人在月经不同时期血液性激素水平呈现不同的变化 ,对肿瘤的发生发展产生一定的影响 ,生存率与血清孕酮含量有关 ,与雌激素、泌乳素的相关性需进一步探讨。
Objective To explore the relationship between surgery and prognosis in different phases of menstrual cycle. Methods The serum prolactin, estradiol, and progesterone concentrations were determined at different stages of the menstrual cycle (follicular phase, corpus luteum phase, and periovulation phase, and peri-menstrual phase), and the relationship with the 3 and 5-year survival period was determined. Results (1) Serum progesterone levels increased significantly during the ovulation and luteal phase; (2) 3 and 5 year survival rates were high in the ovulation period; (3) 3-year survival rate was high in the luteal phase, but there was no difference in the 5-year survival rate. . Conclusions The levels of blood sex hormones in breast cancer patients at different periods show different changes, which have a certain impact on the occurrence and development of tumors. The survival rate is related to serum progesterone levels, and the correlation with estrogen and prolactin needs further discussion.