[目的 ]探讨多元教学法在生物技术制药教学中的应用效果。[方法 ]选取本院2012级医学生物技术专业本科生60名,在一般教学方法基础上应用多元教学法,设立仅采用一般教学法的对照组,课程结束后进行学生满意度评测,并通过闭卷考试鉴定教学效果。[结果 ]学生对本次教学改革效果给与很高评价,考试成绩表明多元教学组成绩与对照组相比明显提高(P<0.05)。[结论 ]多元教学法改提升生物技术制药的教学效果,同时提高了学生的自学能力和科研思维。 [Objective] To discuss the application effect of multiple teaching methods in biotechnology pharmaceutical teaching. [Methods] Sixty undergraduates of 2012 medical biotechnology specialty in our hospital were selected. Based on the general teaching methods, the multiple teaching method was used to establish the control group which only adopted the general teaching method. After the course was finished, the students’ satisfaction was evaluated. Examination appraisal teaching effect. [Results] The students gave high evaluation on the effect of this teaching reform. The test scores showed that the scores of multiple teaching groups were significantly higher than those of the control group (P <0.05). [Conclusions] Multivariate teaching method improves the teaching effect of biotechnology pharmacy, at the same time, it improves students’ self-learning ability and scientific thinking.