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糖尿病足部慢性难愈创面造成了较高的致残率。40%～80%的糖尿病足溃疡合并感染。慢性难愈创面感染的主要特征是混合感染、异位感染、多重耐药菌感染。随着对难愈创面发生机制和创面愈合过程的深入了解以及各种有效地生长因子转入技术、医用新材料和创面治疗新技术如负压创面治疗技术的应用和成熟,难愈创面愈合有望成为现实。现对糖尿病足难愈溃疡患者感染病原菌分布、感染特征、发生机制及目前应用的治疗新技术作一综述。
Diabetic foot chronic refractory wound caused a high rate of disability. 40% to 80% of diabetic foot ulcer infection. The main features of chronic refractory wound infection are mixed infection, ectopic infection, multiple drug-resistant bacterial infections. With the in-depth understanding of the mechanism of refractory wound healing and wound healing, as well as the application and maturity of various effective growth factor transfer technologies, new medical materials and new therapeutic techniques for wounds, such as the treatment of negative pressure wounds, refractory wound healing is expected Become reality. Now the diabetic foot ulcer patients infected with pathogens distribution, infection characteristics, mechanism and application of the treatment of new technologies are reviewed.