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目的：寻找原发性食管单纯腺癌的规律，从而提高患者生活质量和生存率。方法：总结３２例手术病理证实为原发性食管单纯腺癌的临床资料，包括组织学来源，病理组织分型、生物学特性、诊断、外科治疗和综合治疗，分别进行讨论。结果：原发性食管单纯腺癌的预后较食管鳞癌差，仅１例生存３年以上。结论：食管腺癌的综合治疗、主张以手术为主，不提倡常规术前放疗或化疗
Objective: To find the rules of primary esophageal simple adenocarcinoma, so as to improve the quality of life and survival rate of patients. Methods: The clinical data of 32 cases of primary esophageal simple adenocarcinoma confirmed by pathology were summarized, including histological origin, histopathological classification, biological characteristics, diagnosis, surgical treatment and comprehensive treatment. Results: The prognosis of primary esophageal simple adenocarcinoma was worse than that of esophageal squamous cell carcinoma. Only 1 patient survived for more than 3 years. Conclusion: The comprehensive treatment of esophageal adenocarcinoma advocates surgery, but does not advocate routine preoperative radiotherapy or chemotherapy.