The salt-containing extractive distillation column and the salt-containing agent recovery columnfor the 2-propanol/water/ethanediol/KAc system were simulated by the NRTL model and the modified RoseRelaxation method.The simulation results showed that prediction of the salt effect in vapor-liquid equilib-rium and the correlation method (TDCM) of NRTL parameters were suitable for the said system.Fourdifferent distillation technology processes were investigated;the results showed that the salt-containingextractive distillation process was the best one.The simulating design of the extractive distillation columnwas performed under the conditions of different total stage number,feeding location,reflux ratio,amountof mixed agent and concentration of KAc.The results showed that such factors as 17 stages,a feedinglocation at the 9th stage,a reflux ratio of 1.2,and a mixed agent feeding rate of 1.141 kmol/h,might be thebest suited operating conditions.The simulating design was also done for the column for recovering thesalt-containing agent.The simulation method of the salt-containing extractive distillation is simple andeffective in this work. The salt-containing extractive distillation column and the salt-containing agent recovery column for the 2-propanol / water / ethanediol / KAc system were were simulated by the NRTL model and the modified Rose Reaction method. The simulation results showed that prediction of the salt effect in vapor -liquid equilibri rium and the correlation method (TDCM) of NRTL parameters were suitable for the said system. Flowifferent distillation technology processes were investigated; the results showed that the salt-containingextractive distillation process was the best one. The simulating design of the extractive distillation column was performed under the conditions of different total stage number, feeding location, reflux ratio, amount of mixed agent and concentration of KAc.The results showed that such factors as 17 stages, a feeding location at the 9th stage, a reflux ratio of 1.2, and a mixed agent feeding rate of 1.141 kmol / h, might be thebest suited operating conditions. The simulating design was also done for the c olumn for recovering the salt-containing agent. The simulation method of the salt-containing extractive distillation is simple an effect in this work.