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目的:探讨肠胃康保留灌肠治疗中重度放射性直肠炎的临床疗效。方法:将104例放射性直肠炎患者随机分为观察组(52例)和对照组(52例),对照组采用传统灌肠方法,观察组采用肠胃康溶于生理盐水加利多卡因加温至39~41℃保留灌肠。结果:总有效率观察组为94.23%,对照组为80.77%,两组比较,差异有统计学意义(P<0.05)。结论:肠胃康保留灌肠可以使药物直接渗入病变肠壁,局部药物浓度高、作用强,病变愈合更快,而且价格低廉、无不良反应。
Objective: To investigate the clinical efficacy of GGT enema for the treatment of moderate-severe radiation proctitis. Methods: A total of 104 patients with radiation proctitis were randomly divided into the observation group (52 cases) and the control group (52 cases). The control group was treated with traditional enema method. The observation group was treated with gingkang kang dissolved in saline plus lidocaine to 39 ~ 41 ℃ enema retention. Results: The total effective rate was 94.23% in the observation group and 80.77% in the control group. There was significant difference between the two groups (P <0.05). Conclusion: GGT can keep the drug infiltrate into the intestinal wall directly. The local drug concentration is high, the effect is strong, the lesion heal faster, the price is lower, and no adverse reaction occurs.