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目的:探讨滨州市先天性甲状腺功能低下症(以下简称CH)的发病特点,提高滨州市CH的诊疗水平。方法:将2001~2007年滨州市确诊的CH病例进行系统性整理、分类,与其他地区进行横向性比较。结果:2001~2007年滨州市共筛查221 834名新生儿,筛检、确诊147例CH患儿,CH检出率为1/1 509。2001~2006年共失访CH患儿30例,平均失访年龄12.5个月,最主要的失访原因为家长缺乏理解及经济原因。结论:滨洲市CH发病率处在较高水平,且呈现越靠近海边地区CH检出率越高的特点;针对CH患儿失访率偏高的问题,需加强教育、宣传,加大投入,巩固新生儿疾病筛查的成果。
Objective: To investigate the incidence of congenital hypothyroidism (CH) in Binzhou and to improve the diagnosis and treatment of CH in Binzhou. Methods: The CH cases diagnosed in Binzhou from 2001 to 2007 were systematically sorted and classified, and compared with other regions. Results: A total of 221 834 newborns were screened in Binzhou from 2001 to 2007. Among 147 children with CH who were screened and diagnosed, the detection rate of CH was 1/1 509. In 2001-2006, 30 children with CH were lost, The average age for missing persons was 12.5 months. The main reasons for the loss were parents’ lack of understanding and economic reasons. Conclusion: The CH incidence in Binzhou City is at a high level, and the more the detection rate of CH is, the higher the detection rate of CH is. For CH patients with high follow-up loss rate, education, publicity and investment should be stepped up , Consolidate the results of screening newborns disease.