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CD4 4基因蛋白(clusterofdifferentiationCD4 4 )属于黏附分子家族,是分布极为广泛的高度异质性的单链跨膜糖蛋白,能与多种配体、分子结合,参与多种生物学功能。研究发现CD4 4及CD4 4拼接变异体(CD4 4v)在肿瘤扩散与转移过程中起重要作用。一、CD4 4的简介[1 ]CD4 4的编码基因
The CD4 (4) gene belongs to the family of adhesion molecules. It is a highly heterogeneous, single-stranded transmembrane glycoprotein that is widely distributed and can bind to various ligands and molecules and participate in a variety of biological functions. The study found that CD4 4 and CD4 4 splicing variant (CD4 4v) play an important role in the process of tumor proliferation and metastasis. First, the introduction of CD4 4 [1] CD4 4 encoding genes