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目的探讨氟伐他汀与氯吡格雷联合治疗脑梗死的临床效果。方法所选研究对象为2016年2月至2017年2月沈阳市第四人民医院收治的74例脑梗死患者。按照就诊先后顺序,随机分为研究组(氟伐他汀+氯吡格雷)与对照组(常规对症治疗)。对比两组患者的临床疗效以及治疗前后日常生活能力评分、血脂水平变化情况。结果研究组、对照组患者的治疗总有效率分别为97.3%(36/37)、81.1%(30/37),差异有统计学意义(P<0.05);治疗前两组患者血脂水平及日常生活能力评分对比,差异均无统计学意义(均P>0.05);治疗后两组血脂水平及日常生活能力评分对比,研究组各指标均优于对照组,差异均有统计学意义(均P<0.05)。结论在脑梗死患者的临床治疗中,在常规对症治疗基础上加用氟伐他汀和氯吡格雷联合治疗效果理想,还能有效改善患者的血脂水平。
Objective To investigate the clinical effect of fluvastatin combined with clopidogrel in the treatment of cerebral infarction. Methods Selected subjects were 74 cerebral infarction patients admitted to the Fourth People’s Hospital of Shenyang City from February 2016 to February 2017. In accordance with the order of treatment, were randomly divided into study group (fluvastatin + clopidogrel) and control group (conventional symptomatic treatment). Compare the clinical efficacy of two groups of patients before and after treatment and daily living ability score, blood lipid levels. Results The total effective rates of the study group and the control group were 97.3% (36/37) and 81.1% (30/37), respectively, with significant difference (P <0.05). The blood lipid levels and daily (P> 0.05). After the treatment, the blood lipid levels and daily living ability score of the two groups were compared, the indexes of the study group were better than the control group, the differences were statistically significant (P <0.05). Conclusion In the clinical treatment of patients with cerebral infarction, the combination of fluvastatin and clopidogrel combined with conventional symptomatic treatment is effective and can effectively improve the level of blood lipids in patients with cerebral infarction.