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目的评价大剂量地塞米松治疗特发性血小板减少性紫癜疗效和安全性。方法应用大剂量地塞米松与常规剂量泼尼松治疗特发性血小板减少性紫癜比较近期和远期疗效及安全性。结果大剂量地塞米松治疗ITP完全缓解率和远期缓解均优于泼尼松组,不良反应较泼尼松少(P<0.05)。结论大剂量地塞米松治疗特发性血小板减少性紫癜有较好疗效和安全性。
Objective To evaluate the efficacy and safety of high-dose dexamethasone in the treatment of idiopathic thrombocytopenic purpura. Methods The application of high-dose dexamethasone and conventional-dose prednisone in the treatment of idiopathic thrombocytopenic purpura in recent and long-term efficacy and safety. Results The high dose dexamethasone was superior to prednisone in complete remission rate and long-term remission, and the adverse reactions were less than prednisone (P <0.05). Conclusion High-dose dexamethasone treatment of idiopathic thrombocytopenic purpura has good efficacy and safety.