韦格内肉芽肿(Wegener’s granulomatosis)1936年被证实,病因不明。可能与变态反应及自身免疫有关。 1 临床表现本病好发于40～50岁男性,男女之比2∶1,起病缓慢隐袭,上呼吸道症状一般为首发表现,继而累及下呼吸道,严重者累及肾脏,皮肤亦常累及,较少见的有眼、耳、口、心脏、关节及消化道症状。可分局限型和周身型两种。 1.1 局限型韦格内肉芽肿此型较多见,病变仅限于 Wegener’s granulomatosis was confirmed in 1936 and the cause was unknown. May be related to allergies and autoimmunity. 1 Clinical manifestations of the disease occurs in 40 to 50-year-old male, the ratio of men to women 2: 1, onset of insidious onset of upper respiratory symptoms are generally the first manifestation, and then involving the lower respiratory tract, severe kidney involvement, the skin is often involved, Less common eye, ear, mouth, heart, joint and gastrointestinal symptoms. Can be divided into two types of body and type. 1.1 limited type Wegener granulomatous type more common, lesions are limited to