２００１年山东章丘市养鱼池广泛流行肝胆综合症，到６月份，发病面积达到４０００余亩，造成死鱼２５０余吨，重病塘草鱼死亡率达５０％以上，危害严重。为有效控制疫情，章丘市水产站组织技术人员对发病情况进行了详细调查，并在山东省淡水所有关专家的指导下对该病的治疗措 2001 Zhangqiu City, Shandong fish pond widely prevalence of hepatobiliary syndrome, to June, the incidence of more than 4,000 acres, resulting in dead fish more than 250 tons, seriously ill pond grass carp mortality rate of 50% or more, serious harm. In order to effectively control the outbreak, Zhangqiu Aquatic Station technical staff organized a detailed investigation of the incidence, and in Shandong Province, freshwater under the guidance of all the experts on the treatment of the disease measures