论文部分内容阅读
目的：研究子宫颈神经内分泌癌的组织学特性和诊断要点。方法：收集子宫颈神经内分泌癌5例，应用免疫组织化学等方法对其组织学特点进行观察。结果：肿瘤由小细胞组成，形态一致，可弥漫成片或排列呈器官样结构，有一些病例可合并鳞癌或腺癌；免疫组化结果发现，5例突触素和NSE均阳性，4例嗜铬素A阳性，1例嗜铬素A阴性；证实了这一肿瘤的神经内分泌化特征。结论：对宫颈神经内分泌癌的诊断，应采用免疫组化等方法，观察其组织学特点，并与非霍奇金淋巴瘤、胚胎性横纹肌肉瘤、间质肉瘤等鉴别。
Objective: To study the histological characteristics and diagnosis of cervical neuroendocrine carcinoma. Methods: Cervical neuroendocrine carcinoma was collected in 5 cases. Immunohistochemistry and other methods were used to observe the histological features. Results: The tumor consisted of small cells with the same morphology and could diffuse into a piece or arranged in an organ-like structure. Some cases could be associated with squamous cell carcinoma or adenocarcinoma. The immunohistochemistry results showed that all the 5 cases were positive for synaptophysin and NSE, 4 Cases of chromogranin A positive, 1 cases of chromogranin A negative; confirmed the neuroendocrine characteristics of this tumor. Conclusion: The diagnosis of cervical neuroendocrine carcinoma should be used immunohistochemistry and other methods to observe the histological features, and non-Hodgkin’s lymphoma, embryonal rhabdomyosarcoma, interstitial sarcoma and other identification.