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目的:对慢性支气管炎合并肺癌患者临床症状进行分析研究,寻找误诊的原因并最大限度地减少误诊现象,为慢性支气管炎合并肺癌患者的科学治疗寻求更为有效的方法。方法:对本院2005年1月-2011年12月期间收治的19例慢性支气管炎合并肺癌患者作为研究对象,选取其临床治疗资料进行分析,对患者发病特征开展分析研究。结果:对患者运用纤维支气管镜活检、痰瘤细胞检查、刷检以及胸水脱落细胞检查、锁骨上淋巴结活检和经皮肺活检等方式,分别确诊5例、6例、1例、3例、2例、2例,患者中腺癌、鳞癌分别为10例、7例,其余类型2例。患者中5例进行手术治疗并手术后化疗,10例进行化疗并中医中药、免疫治疗,4例进行放疗并免疫治疗、中医中药治疗,确诊治疗后1年、3年、5年以上生存病例理分别为5例、9例、2例,其余3例病发后1年内死于肺癌及其并发症。结论:对于慢性支气管炎患者怀疑合并癌症状况时,及时开展胸部CT、磁共振成像检查,并且通过纤维支气管镜肺活检、肿瘤标记物以及痰病理学等检查,能够准确诊断,最大限度地减少误诊现象。
OBJECTIVE: To analyze the clinical symptoms of patients with chronic bronchitis and lung cancer, find out the causes of misdiagnosis and minimize the misdiagnosis and seek more effective methods for the scientific treatment of patients with chronic bronchitis and lung cancer. Methods: Nineteen patients with chronic bronchitis and lung cancer who were treated in our hospital from January 2005 to December 2011 were selected as the research object. The clinical data were analyzed and analyzed. Results: 5 cases, 6 cases, 1 case, 3 cases, 2 cases were diagnosed by fiberoptic bronchoscope biopsy, sputum tumor cell examination, brush test and pleural effusion cytology, supraclavicular lymph node biopsy and percutaneous lung biopsy. Cases, 2 cases, patients with adenocarcinoma, squamous cell carcinoma were 10 cases, 7 cases, the remaining 2 cases. Five of the patients underwent surgery and postoperative chemotherapy. Ten patients underwent chemotherapy with traditional Chinese medicine and immunotherapy. Four patients were treated with radiotherapy and immunotherapy, one was treated with traditional Chinese medicine. One year, three years, and five years after the diagnosis were confirmed. Respectively, 5 cases, 9 cases, 2 cases, and the remaining 3 died of lung cancer and its complications within 1 year after the onset of disease. CONCLUSIONS: Thoracic CT and magnetic resonance imaging were performed in time in suspected patients with chronic bronchitis and were diagnosed on the basis of bronchofibroscopic lung biopsy, tumor markers and sputum pathology to minimize the possibility of misdiagnosis phenomenon.