Energy is now becoming the bottleneck of urban and regional development. The paper takes Shandong Province, one of the most energy consuming provinces in China, as an example, uses quantity methods such as SPSS (Stastics Package for Social Science) cluster sampling and regression analysis, and applies quantity analysis, to analyze the situation of energy is-sues in Shandong province. The conflicts between the quick industrialization and increasing extensive economic development, between urban population and energy consuming per head, between the infinite energy consuming desire and the low level of managing system, and between the unstable world energy supply and the limited energy storage in China are the main factors of energy crisis in Shandong, which not only results in energy shortage, but also becomes the barrier of economic and social development. In order to ensure sufficient energy supply for Shandong province in the 21st century, we should take countermeasures, such as changing the economic development model, pursuing a multiple and high quality energy strategy, improving the intensive urbanization strategy, and building a scientific energy system.